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Neuroscience

PhD stipend in gut microbiota-derived extracellular vesicles in the gut-brain-metabolic axis

The PhD student will be included as an integrated part of the research activities in the LHMI group, with a special focus on the functional role of gut microbiota-derived extracellular vesicles in disease models. The emphasis will be on the communicative potential of these vesicles in the gut-brain-metabolic axis. The LHMI group operates a state-of-the-art molecular biology laboratory and maintains close collaborations with clinical departments. We work with numerous national and international partners, and our team is multidisciplinary, consisting of molecular biologists, engineers, biomedicine experts, physicians, and laboratory technicians. We are focused on the human microbiome and its impact on various areas of neuroscience and metabolism, including diabetes, depression, autism, ADHD, and Alzheimer's disease.

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PhD position in Implantable Neuroelectronic Devices Research, Development, and Innovation

Develop implantable bioelectronics devices. This is a collaborative project between the Dept. of Neurosurgery at Harvard Medical School (HMS), Dept. of Neurology at Albert Einstein College of Medicine (Einstein), USA, and Dept. of Neuroscience at the University of Copenhagen (KU), Denmark. The enabling technology is a newly invented MEMS microcoil chip, which we named Trinity. In Europe, we are leading this research area. In the long term, our microcoil based implant can be used to treat many illnesses associated with the brain and beyond. We also believe our technology can be used for other neurological illnesses that benefit from local electromagnetic stimulation. The Novo Nordisk Foundation generously supports the project.

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Re-advertisement: Postdoctoral position in Mathematical Modelling of Cognition

The Cognition, Intention, and Action (CoInAct) Research Group and Department of Psychology, Faculty of Social Sciences, University of Copenhagen (UCPH), Denmark, invites applications for a Postdoctoral position in mathematical modelling of cognitive processes to be filled by 1 September 2025 or as soon as possible thereafter. The position is for 2 years. Information about CoInAct can be found at https://psychology.ku.dk/coinact/. Job content The Postdoc will be part of a project entitled Selection in Cognition funded by the Carlsberg Foundation and headed by Professor Søren Kyllingsbæk and Associate Professor Thor Grünbaum. The larger project develops and tests a new theory of basic cognitive selection mechanisms by combining methods and perspectives from experimental psychology, cognitive neuroscience, mathematical modelling, and philosophy (Grünbaum, Oren, & Kyllingsbæk, 2021; Oren, Kyllingsbæk, Dupont, & Grünbaum, 2024). Applicants are asked to situate and develop their research plan within the framework of the Selection in Cognition project. The Postdoc should be a researcher with a strong background in mathematical modelling and is expected to be familiar with formals modelling frameworks such as linear ballistic accumulator models, diffusion models, biased competition models, or Bayesian models. During the employment, the candidate is expected to engage in the development of computational models, model selection, and contribute to the development of experimental paradigms. This will enable us to test and develop our theory of cognitive selection in the domains of task selection, planning, and decision making at both psychological and neurophysiological levels. The successful candidate will be working in close collaboration with cognitive psychologists and philosophers, and other cognitive scientists, and should be interested in the development of new computational models, experimental paradigms, and theories. It is expected that the successful candidate will be present, part of the team, and partake in the activities at CoInAct on a daily basis. The Postdoc will be physically located at the Cognition and Neuropsychology research cluster https://psychology.ku.dk/research/research_clusters/cognition-and-clinical-neuropsychology/, at the Department of Psychology, University of Copenhagen.

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One or more Postdoctoral Research Fellowships in IT Projects and IT Project Management

Recipient of the Villum Kann Rasmussen Professorship, Bent Flyvbjerg's research group at The Danish Institute for IT Program Management is seeking one or more Postdoctoral candidates. The main areas of research are IT projects and IT program management. Applicants are not required to have research experience in these fields. Candidates with backgrounds in statistics, economics, business administration, geography, biology, engineering, physics, or similar fields are encouraged to apply. The Postdoctoral Research Fellow will be responsible for both their own research and publications, as well as supporting other research activities within DIIP, predominantly those of VKR Professor Bent Flyvbjerg.

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Assistant Professor in Neural Engineering and Neurophysiology

Sensory processing difficulties are common in clinical conditions such as autism spectrum disorder and attention deficit hyperactivity disorder(ADHD). However, the neural mechanism behind this impairment is not fully understood and a direct measure of these difficulties in unavailable. We are looking for a candidate that will investigate the mechanism behind sensory processing disorders in neurodevelopmental disorders using neural engineering methods with the perspective of translating the obtained results into digital health solutions. Sensory processing anomalies will be investigated in adults and children through recording and analysis of non-invasive measurements of neural activity(EEG) and/or psychophysical assessment. Advanced signal analysis, including e.g. machine learning techniques, should be used for the assessment and evaluation of the obtained information.

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Postdoc in Neurobiology

The Genome Biology Research Unit at the Department of Molecular Medicine, SDU, invites applications for a position as postdoc in Neurobiology in the laboratory of DNRF Chair and Novo Nordisk Faculty Professor Vijay Tiwari (https://www.tiwarilab.com/ ). The position is available - initially for six months - from June 1, 2025, or as soon as possible thereafter - with the possibility of extension. The postdoc will lead research on deciphering gene regulatory mechanisms underlying brain development and its disruption in neurodevelopmental disorders. The group addresses these aims by employing state-of-the-art neurobiology in combination with genomics and computational biology approaches. The research in Tiwari lab is supported by a cutting-edge research environment as well as globally known local and international collaborators. To learn more, please refer to the selected publications from the Tiwari lab: JCI Insight. 2025 Jan 9;10(1):e184518; Science Advances, 2024, Jun 7;10(23):eadn1640; EMBO Mol Medicine, 2024, Apr; 16(4):823-853; Nature Communications, 2024, in press; npj Precision Oncology, 2024, Mar 12;8(1):64; Nature Cell Biology, 2022, 24, 1265–1277; Genes & Development, 2020, Sep; 34(17-18):1190-1209; Nature, 2019, Mar; 567(7746):113-117; Cell Stem Cell, 2018, Oct 4; 23(4):557; Nature Communications, 2017 Nov 15;8(1):1523; The EMBO Journal, 2016 Jan 4;35(1):24-45; J Cell Science, 2015 Dec 1;128(23):4380-94; The EMBO Journal, 2015 Aug 13;34(16):2162-81; Genome Research, 2015 Sep;25(9):1309-24; Nature Communications, 2013, Sep 27; 4:2478; Cancer Cell, 2013, 23, 768-783; PNAS, 2012 Apr 17;109(16): E934-43; Nature Genetics, 2012 Jan; 18;44(1):94-100; Nature, 2011 Dec 14;480 (7378):490-5. You will Lead research on investigating gene regulatory mechanisms underlying brain development and its disruption in neurodevelopmental disorders Design research projects and support in establishing complex molecular biology protocols Perform in vitro and in vivo (animal models) experiments as necessary Support research and development activities within the group Support the group leader in everyday routines including training new group members Maintain accurate and detailed records of all research activities within the group Collaborate with internal and external partners Engage in supervision and teaching as required Conduct collaborative research and interact with a broad range of colleagues and researchers Essential qualifications PhD in neurobiology, cell biology, molecular biology, epigenetics or biochemistry. At least one first-author publication, accepted or submitted. Previous experience with cell culture and molecular biology assays such as Gene cloning, RNA isolation, qPCR, FAC-sorting, Immunofluorescence assay, ChIP or CUT&RUN methods. Strong analytical, organizational, and record-keeping skills Proficient computer skills, including MS Office and research software programs Interest in working in a multidisciplinary and multicultural team Willing to collaborate with internal and external collaborators as well as support group members Experience and interest in supervision Expectations of qualifications Experience in mouse experiments and tissue analysis by immunohistochemistry. Familiarity with iPSc culture and cerebral organoids. Experience with perturbation-based functional analysis (e.g. shRNA, CRISPR-Cas9) We offer The possibility to engage in high-impact, multidisciplinary research A stimulating, diverse and international research environment An initial contract for six months, with the possibility of long-term extension Advanced training opportunities Highly motivated research team and international collaborations Access to state-of-the-art equipment and facilities A supportive scientific and social network, including mentoring and career development A competitive salary and social benefits (e.g. health coverage, parental leave, social security etc.) Support with practical, social, and legal aspects (e.g. housing, visa, tax etc.) through our international staff office (ISO) and the department

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Clinical professor of Psychiatric Bioinformatics (fixed-term, 5 years)

Clinical Professor of Psychiatric Bioinformatics (Fixed-Term, 5 Years) Department of Clinical Medicine Faculty of Health and Medical Sciences University of Copenhagen The University seeks to appoint a clinical professor of Psychiatric Bioinformatics to commence as soon as possible. The externally funded professorship is combined with a position as senior researcher at the Psychiatric Center Sct. Hans, Copenhagen University Hospital - the Mental Health Services in Capital Region of Denmark (Institute of Biological Psychiatry). It is a requirement for appointment that the applicant is accepted for both the professorship and the consultancy. In order to be considered for the position, the applicant must send two applications: one to the Faculty (the professorship) and one to the hospital (the position as senior researcher) cf. the simultaneously advertised position. This also applies to applicants who are already employed at the Hospital. Please fin the advertisement for the position as senior researcher here Senior researcher position combined with a clinical professorship in Psychiatric Bioinformatics Both the professorship and the consultancy will be financed by the Psychiatric Center Sct. Hans, Copenhagen University Hospital. Find information about the department. Job description In the consideration of applications for the professorship, the main emphasis will be on the applicant's ability to document a high level of original scientific work at an international level within the area of Psychiatric bioinformatics and neuroscience broadly. The professor’s responsibilities will primarily consist of: Research, including publication/academic dissemination - The professorship entails research within the field of Psychiatric bioinformatics, which seeks to map and understand molecular and cellular biological processes that underlie mental illness, and ultimately aims to inform prevention, diagnostics and treatment of mental disorders Research-based teaching, including associated examination and teaching at the School of Medicine, Master in Neuroscience and Master in Personal Medicine Research leadership, including guidance and supervision of researchers and medical students and head the research group within psychiatric bioinformatics Obligation to share knowledge with the rest of society, including participation in public debate Academic assessments

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PhD Project: Evaluating focused ultrasound as a treatment and scientific tool to treat and investiga...

The Dept. of Neurosurgery, Dept. of Clinical Medicine, Aarhus University is offering a fully funded PhD scholarship with expected enrollment 1 September 2025. The project will be carried out at Dept. of Neurosurgery, Aarhus University Hospital and conducted in close collaboration with the Departments of Neurology, Nuclear Medicine & PET and Neuroradiology. Project description The main purpose of this project is to assess the effect of MR-guided focused ultrasound thalamotomy (MRgFUSTh) in a well-characterized cohort of Parkinson’s Disease (PD) patients with tremor. While MRgFUSTh has long-lasting effects in patients with essential tremor, approximately 20% of patients with PD experience recurrence of the symptoms within 1-2 years of the treatment. A clinical audit suggests that patients with tremor symptoms which decrease upon levodopa treatment may have a lower chance of achieving a long-lasting clinical response to MRgFUSTh treatments. We aim to investigate how brain circuit dysfunctions, including dopaminergic dysfunctions, affect the clinical efficiency of MRgFUSTh in PD patients. We expect the results from this study will help identify pharmacological/imaging biomarkers at baseline that could be predictive of a favourable MRgFUSTh outcome in PD patients and, therefore, influence and improve how we select patients for the procedure. We also expect that results from this study will have important clinical and health-economic implications, as they will improve the current understanding of the clinical benefits and side-effect profile of unilateral MRgFUSTh for PD tremor which can lead to a better selection of PD patients for this procedure, and, possibly, identify strategies to improve outcomes in all patients.

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Postdoc in Tinnitus Research and Hearing Rehabilitation

The Hearing Systems Section at the Department of Health Technology (DTU Health Tech) at the Technical University of Denmark (DTU) and Copenhagen Hearing and Balance Center (CHBC) at the Ear, Nose and Throat (ENT) & Audiology Department at Rigshopitalet, Copenhagen University Hospital, Denmark, seek a qualified candidate for a 2-year postdoc position. The joint position is within the areas of tinnitus research and hearing rehabilitation and is based both at DTU and CHBC. Your primary focus will be to strengthen the department’s expertise in tinnitus research and hearing rehabilitation. You will use neuroimaging and psychoacoustic tests to gain a better understanding of tinnitus mechanisms and explore improved tinnitus treatments. You will collaborate closely with colleagues and work with both academic and clinical partners in Denmark and internationally.

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Postdoc in Epigenetics

Applications are invited for a position of postdoc in Epigenetics in the laboratory of DNRF Chair and Novo Nordisk Faculty Professor Vijay Tiwari (https://www.tiwarilab.org/ ). The position is available - initially for six months - from July 1, 2025, or as soon as possible thereafter - with the possibility of extension for three or more years. The postdoc will lead research on gene regulatory mechanisms in development and disease and will support Professor Tiwari in smooth running of the laboratory at various levels. The group employs cutting-edge molecular biology, epigenetics and genomics tools in combination with computational biology approaches to generate comprehensive models of gene regulation during development and diseases such as cancer and neurodevelopmental disorders.

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Postdoctoral position within molecular aspects of Parkinson’s Disease

You will work with antibodies, small molecules and peptides that target the cytotoxic oligomer of α-synuclein involved in Parkinson’s Disease. This is part of a vibrant multidisciplinary network collaboration headed by Prof. Daniel Otzen, AU, and including collaborators Dr. Simon Glerup (Draupnir and AU), Prof. Mads Hartvig Clausen (DTU) and U Copenhagen scientists Dr. Céline Galvagnion, Prof. Nikos Hatzakis, Prof. Martin Lauritzen and Dr. Krzysztof Kucharz. Work includes purification and biophysical analysis of monoclonal antibodies, biophysics of α-synuclein aggregation and biophysical and cellular assays to screen α-synuclein interactions with antibodies, liposomes and other molecules. You will interact with experts within stem cells, liposome single-particle microscopy and 2-photon microscopy for blood-brain-barrier transport imaging. More information can be found in a brief overview of the research consortium’s strategies here and original articles here (antibodies) and here (screening).

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PhD AI:Cybernetics Lab Smarter Human-Robot Collaboration Through Artificial Intelligence

We live in a world where robots are increasingly used in industry and healthcare but making them work naturally with humans remains a challenge. AI:Cybernetics develops a new kind of control system, where AI combines human signals (like muscle activity) with awareness of the environment (such as camera input). Imagine a robotic, prosthetic hand that automatically adjusts to the object you want to grab- without you needing to consciously control every movement. The same principle applies to robot arms helping with assembly tasks. The goal is intuitive and efficient teamwork between people and robots. The goal of AI:Cybernetics lab is to enable human-machine interfacing for robotic applications where humans and robots share control (e.g. cobots in industry and bionic limbs in health). This requires comprehensive integration of many data sources coming from the user, robot, and environment. This challenge can be addressed only using advanced AI. This lab will develop a radically new paradigm for human control of complex robotic systems with high levels of agency and minimal cognitive effort. The lab is looking for candidates for the following four stipends:

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Assistant professor in biomedicine with teaching commitments in macroscopic anatomy

The ideal candidate will contribute with a robust research portfolio within the field of tissue research. The unit focuses primarily on pathophysiological changes in muscle, tendon, and connective tissues in patients with CNS lesions and neuromuscular diseases. However, research in other tissue-related areas—such as sports medicine, cardiology, dermatology, tissue engineering or other—may also align with the scope and objectives. Preferred methodologies include 3D imaging, 3D microscopy, plastination, and histology. Familiarity with one or more of these techniques will be expected, along with the potential to introduce complementary methods that enhance the units research capabilities. Research infrastructure with new labs, several core facilities within imaging, transcriptomics and animal models will be available and are physically close to the anatomy unit. Ability to secure external funding is crucial for the research. Close collaborations will be expected within the unit, the department, and with Odense University Hospital. Establishment of strong international collaborations of benefit to the unit as well as the department will be expected as well. Participation in assessment work and other faculty duties will be part of the position. Moreover, profiling this research area in the public eye will be an important task.

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Postdoc in cellular biology at the Department of Drug Design and Pharmacology Faculty of Health and ...

The Galvagnion group is looking for a highly motivated and dynamic researcher for a 8-month post-doctoral position in cellular biology in “Protein-membrane interactions in health and disease” in May 30, 2025 or shortly after. Preference will be given to candidates with a strong expertise in fibroblasts and stem cell culture maintenance and differentiation as well as biochemistry. The purpose of the postdoc is to analyze patients’ bio-samples to reveal a molecular signature that, together with clinical data, will enable to stratify high risk iRBD individuals for conversion into different types of alpha-synucleinopathies. This project is part of the interdisciplinary consortium DEEPEN-iRBD including the Luxembourg Parkinson’s study. Information on the department can be found at: https://drug.ku.dk

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Postdoctoral position in experimental cognitive psychology

A postdoc position is available in the newly established project on experimental investigation and computational modelling of cognitive control and flexibility funded by the Independent Research Council. The project is located at the Psychology Department at the University of Copenhagen (see psy.ku.dk) and directed by PI Associate Professor Anders Petersen. The expected starting date is 1 June 2025. The position is available for two and a half years. Duties and Responsibilities The successful candidate will work on implementing and running computer-based psychological experiments investigating cognitive control and task-switching. The experiment will involve behavioural measures, eye tracking, pupillometry, and EEG. As a large part of the project revolves around computational models of cognition, the candidate will also, in collaboration with the research team, contribute to the development and testing of neural network models of perceptual and neural processes underlying cognitive control. The successful candidate will take a full and active role in the daily life of the research group, including attending workshops, reading groups and lab meetings.

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Clinical Professor of Psychiatry with a special focus on Psychotherapy (Fixed-Term, 5 Years)

The University seeks to appoint a clinical professor of Psychiatry with a special focus on psychotherapy to commence as soon as possible. The externally funded professorship is combined with a consultancy or senior researcher at Center Stolpegård, Copenhagen University Hospital - Mental Health Services CPH in the Capital Region. It is a requirement for appointment that the applicant is accepted for both the professorship and the consultancy/position as senior researcher. In order to be considered for the position, the applicant must send two applications: one to the Faculty (the professorship) and one to the hospital (the consultancy/senior researcher position) cf. the simultaneously advertised position of the consultancy/position as senior researcher. This also applies to applicants who are already employed at the Hospital. Please find the advertisement for the consultancy/position as senior researcher here. Both the professorship and the consultancy will be financed by Center Stolpegård, Copenhagen University Hospital - Mental Health Services CPH. Find information about the department.

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PhD Scholarship in Photoacoustic Optical Fiber Devices for in vivo Applications - DTU Electro

If you want to establish your career as an early-stage neuro-engineer and are currently looking for the best possible foundation for your dreams and ambitions, it is right here in front of you. With this PhD position, we offer you the possibility of establishing your career as a scientist in advanced photoacoustic neural interfaces for the central nervous system. You will be working at DTU Electro, in the Neural Devices and Gas Photonics group in close collaboration with the world-leading group Prof. Lei Wei from Nanyang Technological University in Singapore. They are seeking a highly motivated and talented candidate for a PhD position to join their team and contribute to their efforts in developing next-generation neural devices for controlling the brain activity. You will work on an innovative project that involves the development and characterization of novel piezoelectric materials, optical fiber fabrication using thermal drawing process, integration of the developed interfaces with photoacoustic imaging setups, and in vivo evaluation of the interfaces for stimulation, recording and imaging of movement disorders in the motor cortex of the brain. Such an interface, which currently does not exist, will be capable of providing important information on how the brain works while having a high potential for clinical translation for the treatment of brain diseases such as Parkinson’s. This position offers a unique opportunity to engage in the field of neurophotonics, collaborate with WEI group in Singapore and Department of Neuroscience of University of Copenhagen. The PhD student will become part of the DTU and NTU collaboration with expertise in optical materials, design, fiber fabrication and in vivo investigations. Responsibilities and qualifications While existing methods for stimulation and imaging of brain activity constitute an important tool for medical doctors and neuroscientists, there are still significant bottlenecks towards treating major neurological diseases. For instance, while optogenetics is a powerful method to control neurons, genetic manipulation is required, imposing practical limitations on its clinical translation. On the other hand, calcium imaging offers limited temporal resolution because traditional calcium indicators have relatively slow kinetics, which means they cannot accurately capture rapid changes in neural activity. This PhD project will exploit the development of a novel bi-directional stimulation and imaging interface by utilizing an alternative neuromodulation approach to control brain activity based on photoacoustics. In this process, light pulses are absorbed by brain tissue, causing transient heating and thermal expansion and generating broadband ultrasound signals. The ultrasounds are then collected back from the same interface for image reconstruction. Photoacoustic imaging is a powerful method for high-resolution and deep tissue imaging because it combines the high contrast of optical imaging with the high spatial resolution of ultrasound imaging. Your overall focus will be developing photoacoustic fiber probes for neurostimulation, recording and imaging of the brain activity all-at-once. Your primary tasks will be: Identify the most suitable piezoelectric materials for the development of the fiber probes Simulate the optical properties of the photoacoustic fibers Fabricate and characterize in vitro the photoacoustic fiber probes Conduct animal experimentation Applying the developed probes for in vivo investigation with emphasis in the motor system Supervise BSc and MSc student projects Data analysis, writing of scientific articles and presentations at conferences and meetings. Participate in outreach activities including, but not limited to, social media updates, participation in public events and campaigns, as well as dissemination to popular press. Your required qualifications and skills are: Excellent English communication skills, both spoken and written. Self-motivation in research and innovation. Ability to work independently while effectively collaborating with partners. ‘ A master level education in the fields of materials, optical fiber technology, electrophysiology and imaging Experience in simulation tools such as COMSOL and Zemax including MATLAB coding You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree. As an ideal candidate, you should also have one or more competences below: Experience in material characterization and optical fiber fabrication using thermal drawing process. Optical characterization of fiber devices Experience with piezoelectric materials and photoacoustics Knowledge with imaging techniques and electrophysiology Experience with in vivo experiments in acute and chronic settings The ability to work independently while effectively collaborating with other team members The exact research activities will be continuously adapted to ensure high relevance and impact.

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